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AMVUTTRA® (vutrisiran) ‘Play by Play’ Initiative Highlights Former Athletes’ Stories to Shine a Light on the Often-Missed Signs of ATTR-CM

Business Wire•29/09/2026•09:00 ET
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Key Highlights

  • ➤Alnylam (ALNY) launches U.S. “Play by Play” ATTR-CM educational initiative
  • ➤AMVUTTRA reduces cardiovascular mortality, hospitalizations and urgent heart failure visits
  • ➤AMVUTTRA administered quarterly via subcutaneous injection for ATTR-CM patients
  • ➤AMVUTTRA reduced all-cause mortality and recurrent CV events versus placebo through 36 months

Expert Statements

Tolga Tanguler, Chief Commercialization Officer at Alnylam

“The power of football is built play by play, and strength in silencing with AMVUTTRA is built on the same principle: making precise interventions where they matter”

Tolga Tanguler, Chief Commercialization Officer at Alnylam

“Just as success on the field is built one play at a time, we believe that transformative impact in medicine starts with precisely targeting the drivers of disease.”

Tolga Tanguler, Chief Commercialization Officer at Alnylam

“By harnessing RNAi to silence TTR at the source of disease, Alnylam is helping change what's possible for patients and their teams.”

Pete Shaw, Former professional football player living with ATTR-CM

“I spent my career learning how to read the field and react to what was happening around me. But when it came to my own health, I didn’t recognize that the symptoms I was experiencing could be something serious and progressive.”

Pete Shaw, Former professional football player living with ATTR-CM

“That’s why I’m sharing my story. If it helps even one person pay closer attention to changes in their health, ask questions, or start a conversation with their doctor, then sharing my experience is worth it.”

Rajeev Mohan, Director, Advanced Heart Failure Program, Scripps Clinic, and clinical cardiologist and heart failure specialist

“Early diagnosis is one of the most important factors in the management of this disease.”

Rajeev Mohan, Director, Advanced Heart Failure Program, Scripps Clinic, and clinical cardiologist and heart failure specialist

“Pete’s journey underscores why awareness matters. An earlier diagnosis allows patients to have timely discussions about available treatment options and develop a management plan tailored to their needs.”

AMVUTTRA(®) (vutrisiran) ‘Play by Play’ Initiative Highlights Former Athletes’ Stories to Shine a Light on the Often-Missed Signs of ATTR-CM

– Launching on World Heart Day, Retired Professional Football Player Pete Shaw Shares How Symptoms Attributed to Football and Aging Led to a Delayed ATTR-CM Diagnosis –

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