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BioAge Labs Reports Third Quarter 2026 Financial Results and Provides Business Updates

Globe Newswire•05/11/2026•16:30 ET
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Key Highlights

  • ➤QUELL-CV completed enrollment; topline data anticipated in Q4 2026
  • ➤Cash, equivalents, and marketable securities totaled $352.3 million
  • ➤Net loss widened to $33.5 million, or $0.73 per share
  • ➤QUELL-DME dosed first participant; topline results expected in second half of 2027
  • ➤APJ agonist program remains on track for IND submission by year-end 2026

Expert Statements

Kristen Fortney, CEO and co-founder of BioAge

“NLRP3 is a key switch that turns on inflammation and drives multiple diseases. Injectable drugs that block two major inflammatory signals, IL-1 and IL-6, are already approved for multiple indications, but a once-daily pill that works earlier in the process—and also lowers IL-18 and reduces harmful inflammatory cell death—could help many more people. That is the opportunity we are pursuing with BGE-102”

Kristen Fortney, CEO and co-founder of BioAge

“BGE-102 has a potential best-in-class profile: in Phase 1, it suppressed IL-1β by up to 98% with once-daily dosing and was well tolerated. In addition, the compound showed exceptional tissue penetration into the eye and brain. We dosed the first patient in our Phase 2 eye-disease study, QUELL-DME, in September. The primary endpoint is change in best-corrected visual acuity, the same endpoint used for approval of existing therapies, so a positive result could support a streamlined path into a pivotal trial. Our Phase 2 cardiovascular study, QUELL-CV, is fully enrolled, and we expect the results later this year to inform the optimal dose and show how BGE-102 could affect a range of metabolic and inflammatory markers. With a strong cash position, we are well positioned to advance BGE-102 and our apelin and other programs.”

First participant dosed in QUELL-DME, a Phase 2 trial of BGE-102, a potential best-in-class oral NLRP3 inhibitor, in diabetic macular edema; topline results anticipated in the second half of 2027

QUELL-CV, a Phase 2 dose-ranging trial of BGE-102 in adults with obesity and elevated baseline inflammation, completed enrollment; topline data anticipated in the fourth quarter of 2026

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