Nxera Pharma Operational Highlights and Consolidated Results for the Third Quarter 2026

Chris Cargill, President and CEO of Nxera Pharma

“During the third quarter of FY2026, we continued to build on the progress made in the first half, focusing on growing our business and enhancing the value of our pipeline. In Japan, we remained focused on maximizing the value of PIVLAZ® and QUVIVIQ®. We also made important progress across our partnered programs. Under our collaboration with Neurocrine Biosciences Inc. (“Neurocrine”), we achieved a US$10 million milestone following progress in the development of NBI-1117567, an M1 receptor agonist for cognitive impairment associated with Alzheimer’s disease. A further US$8.6 million milestone was achieved following late-stage development progress in the orexin receptor 2 (OX2R) agonist program originating from our collaboration with Centessa Pharmaceuticals Limited (“Centessa”), which was acquired by Eli Lilly and Company (“Lilly”). These achievements demonstrate how assets originating from our drug discovery technology are generating revenue as they advance through development with our partners. Since the end of the third quarter, we have continued to advance our business in Japan and the broader Asia-Pacific region. In October, we submitted a Marketing Authorization Application in South Korea for vamorolone for the treatment of Duchenne muscular dystrophy (DMD), marking an important step towards bringing a new treatment option to patients in that territory. We also entered into an exclusive license, supply and commercialization agreement with Synmosa Biopharma Corporation (“Synmosa”) for QUVIVIQ® across eight Asia-Pacific markets, establishing a foundation to bring this medicine to more patients. In addition, we exercised our option to license the Fabry disease candidate lucerastat from Idorsia Pharmaceuticals Ltd. (“Idorsia”), strengthening our late-stage rare disease pipeline in Japan and the broader Asia-Pacific region. These achievements demonstrate that our drug discovery, development and partnering strategy is delivering tangible results and strengthening the foundation for future growth. We remain focused on growing our commercial business in Japan and the broader Asia-Pacific region, advancing our partnered programs and maximizing the value of our proprietary pipeline, as we continue to drive sustained growth and value creation for patients and shareholders.”