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Omada Health to Present Peer-Reviewed Research on Improving Weight Loss and Body Composition During GLP-1 Treatment at World Obesity and Weight Management Congress

Globe Newswire•20/10/2026•09:00 ET
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Key Highlights

  • ➤Omada members lost 6.0% of starting body weight versus 3.3% with usual care
  • ➤Omada members reduced body fat percentage 3.3 points versus 1.6 points
  • ➤Omada members increased muscle mass percentage 0.6 points versus 0.2 points
  • ➤245 adults with obesity participated after starting GLP-1 treatment
  • ➤Depression and anxiety symptoms fell roughly 30%, significantly more than usual care

Expert Statements

Thomas Tsang, MD, MPH, Chief Medical Officer at Omada Health

“GLP-1 care is about more than how much weight you lose. It’s about the quality of the weight loss, as losing too much muscle can make it harder to keep the weight off long-term.”

Thomas Tsang, MD, MPH, Chief Medical Officer at Omada Health

“Too many people are left to manage side effects, exercise, and nutrition on their own once GLP-1 treatment starts. This study suggests that clinical support between doctor visits can help people achieve greater weight loss and better body composition, and protect their muscle mass.”

SAN FRANCISCO, Oct. 20, 2026 (GLOBE NEWSWIRE) -- Omada Health (Nasdaq: OMDA), the virtual between-visit healthcare provider, announced it will present research at the World Obesity and Weight Management Congress (WOC 2026) in Boston showing that members of its GLP-1 Care Track lost more weight and experienced greater improvements in body composition than GLP-1 users receiving usual care. The findings were recently published in the peer-reviewed journal Diabetes, Obesity and Metabolism.¹

GLP-1 medications can produce rapid weight loss,(2) but lean mass can account for 30% or more of the weight lost.(3,4) Lean mass is critical for overall health, as losing lean mass may contribute to reductions in resting metabolic rate(5), impaired physical function and greater susceptibility to weight regain,(6) as well as an increased risk for sarcopenia,(7) frailty, and bone loss.(6,8) While exercise and resistance training are known to be effective strategies for increasing fat loss while protecting lean mass,¹ much less is known about whether virtual care programs can improve body composition outcomes for people taking GLP-1 medications.

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