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Precision BioSciences Reports Third Quarter 2026 Financial Results and Provides Business Update

Business Wire•03/11/2026•07:01 ET
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Key Highlights

  • ➤Cash balance $108 million; runway expected through 2028
  • ➤PBGENE-HBV abstract releases November 5; late-breaking AASLD presentation November 8
  • ➤First patient dosed with PBGENE-DMD; initial safety data targeted for year-end 2026
  • ➤Q3 net loss $7.6 million, or $(0.28) per share
  • ➤iECURE’s ECUR-506 cut hyperammonemic event rate 57% in updated low-dose data

Expert Statements

Michael Amoroso, Chief Executive Officer of Precision BioSciences

“We entered 2026 with a clear plan to deliver multiple important clinical and operational milestones this year and we have made significant progress executing against that plan. In the third quarter, we continued to advance PBGENE-HBV in the ELIMINATE-B trial for chronic hepatitis B and are very excited about the opportunity to present important clinical data in a late-breaking oral presentation at the upcoming AASLD Liver Meeting on November 8(th) at 2:15pm MST. The oral presentation will be delivered by our ELIMINATE-B lead investigator, Man Fung Yuen, MD, Ph.D., Chair Professor of The University of Hong Kong and the Chief of the Division of Gastroenterology and Hepatology, Queen Mary Hospital”

Michael Amoroso, Chief Executive Officer of Precision BioSciences

“The third quarter also marked an important milestone for Precision BioSciences and more importantly for the children who live with Duchenne muscular dystrophy (DMD). Our team alongside our investigators commenced dosing of the first patient in the FUNCTION-DMD trial. PBGENE-DMD is a novel, first and only gene editing approach designed to restore near full-length functional dystrophin in patients with DMD by utilizing the body’s native dystrophin gene, restoring dystrophin protein expression after excising a frequently-mutated part of the gene, known as the hotspot region. Based on feedback from patient families, advocacy groups, and DMD physicians, we have received broad support and excitement for this approach”

Michael Amoroso, Chief Executive Officer of Precision BioSciences

“We remain on track to deliver data updates from both programs by year end, supported by a financial position that provides expected runway through 2028 and through key clinical inflection points.”

Precision BioSciences Reports Third Quarter 2026 Financial Results and Provides Business Update

- PBGENE-HBV late-breaking oral presentation for ELIMINATE-B trial at AASLD's The Liver Meeting(®) 2026 on November 8; data abstract scheduled for release November 5 -

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