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Tyra Biosciences Reports Third Quarter 2026 Financial Results and Recent Highlights

PR Newswire•10/11/2026•08:00 ET
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Key Highlights

  • ➤SURF302 60 mg QD produced 79% ORR and 64% BOR CR among 14 patients.
  • ➤Single-marker SURF302 patients achieved 100% ORR and 75% BOR CR at 60 mg QD.
  • ➤SURF303’s first participant achieved complete response at three months with 60 mg QD.
  • ➤TYRA completed a $400 million financing in September 2026.
  • ➤Cash, equivalents and marketable securities totaled $700.5 million, funding operations through 2030.

Expert Statements

Todd Harris, President and Chief Executive Officer of TYRA

“2026 has been a defining year for TYRA. With the initial results from SURF302 in the ablative setting, we believe dabogratinib has the potential to be the first oral FGFR3-selective inhibitor in intermediate-risk non-muscle invasive bladder cancer (IR NMIBC), reinforcing our conviction in the potential of precision FGFR3 inhibition to fundamentally change the treatment paradigm for patients.”

Todd Harris, President and Chief Executive Officer of TYRA

“For too long, patients have faced a cycle of repeated procedures and surveillance, often simply waiting for their cancer to recur. We believe dabogratinib has the potential to break this cycle by offering a differentiated, first-in-class oral product candidate that could transform how patients and physicians manage this chronic, recurrent disease.”

Todd Harris, President and Chief Executive Officer of TYRA

“With a strengthened balance sheet following our $400 million financing, TYRA is entering its next phase of growth from a position of strength. We now have the financial resources to advance our dabogratinib 3x3 strategy through late-stage clinical development. As we prepare for regulatory engagement and planned Phase 3 development, we believe the opportunity for a highly selective, oral FGFR3 inhibitor has never been clearer. We look forward to building on our recent momentum as we work to establish dabogratinib as a potentially transformative therapy for patients with FGFR3-driven diseases.”

Tyra Biosciences Reports Third Quarter 2026 Financial Results and Recent Highlights PR Newswire

Reported initial Phase 2 SURF302 results for oral dabogratinib in FGFR3-altered low-grade IR NMIBC patients

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