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Xencor to Host Webcast to Discuss Results From the Phase 1 Study of XmAb819 in Advanced Clear Cell Renal Cell Carcinoma

Business Wire•19/10/2026•07:01 ET
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Key Highlights

  • ➤XmAb819 Phase 1 results will be presented at ESMO Congress 2026
  • ➤Xencor plans a registration-enabling XmAb819 monotherapy study in 2027
  • ➤Intravenous expansion cohorts support dose selection for planned Phase 3 study
  • ➤Subcutaneous XmAb819 dose escalation in advanced ccRCC remains ongoing
  • ➤ENPP3+ colorectal, lung and papillary renal cancer sub-study opened in Q2 2026

Expert Statements

Sumanta Pal, Professor and Vice Chair of Academic Affairs, City of Hope Comprehensive Cancer Center

“Phase 1 results of XmAb819, a novel ENPP3 x CD3 bispecific, in advanced clear cell renal cell carcinoma (ccRCC)”

Xencor to Host Webcast to Discuss Results From the Phase 1 Study of XmAb819 in Advanced Clear Cell Renal Cell Carcinoma

Xencor, Inc. (NASDAQ:XNCR), a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases, will host a webcast on Monday, October 26 at 7:00 a.m. EDT (4:00 a.m. PDT) to discuss results from the Phase 1 Study of XmAb819, an ENPP3 x CD3 T-cell engaging bispecific antibody, in development for patients with advanced clear cell renal cell carcinoma (ccRCC).

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